Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli

Opiates such as morphine and codeine are mainly obtained by extraction from opium poppies. Fermentative opiate production in microbes has also been investigated, and complete biosynthesis of opiates from a simple carbon source has recently been accomplished in yeast. Here we demonstrate that Escheri...

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Detalles Bibliográficos
Autores principales: Nakagawa, Akira, Matsumura, Eitaro, Koyanagi, Takashi, Katayama, Takane, Kawano, Noriaki, Yoshimatsu, Kayo, Yamamoto, Kenji, Kumagai, Hidehiko, Sato, Fumihiko, Minami, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748248/
https://www.ncbi.nlm.nih.gov/pubmed/26847395
http://dx.doi.org/10.1038/ncomms10390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748248/
https://www.ncbi.nlm.nih.gov/pubmed/26847395
http://dx.doi.org/10.1038/ncomms10390

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