Highly efficient optogenetic cell ablation in C. elegans using membrane-targeted miniSOG

The genetically encoded photosensitizer miniSOG (mini Singlet Oxygen Generator) can be used to kill cells in C. elegans. miniSOG generates the reactive oxygen species (ROS) singlet oxygen after illumination with blue light. Illumination of neurons expressing miniSOG targeted to the outer mitochondri...

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Detalles Bibliográficos
Autores principales: Xu, Suhong, Chisholm, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748272/
https://www.ncbi.nlm.nih.gov/pubmed/26861262
http://dx.doi.org/10.1038/srep21271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748272/
https://www.ncbi.nlm.nih.gov/pubmed/26861262
http://dx.doi.org/10.1038/srep21271

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