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Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms

Protein N-terminal acetylation is an ancient and ubiquitous co-translational modification catalyzed by a highly conserved family of N-terminal acetyltransferases (NATs). Prokaryotes have at least 3 NATs, whereas humans have six distinct but highly conserved NATs, suggesting an increase in regulatory...

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Detalles Bibliográficos
Autores principales: Rathore, Om Singh, Faustino, Alexandra, Prudêncio, Pedro, Van Damme, Petra, Cox, Cymon J., Martinho, Rui Gonçalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748286/
https://www.ncbi.nlm.nih.gov/pubmed/26861501
http://dx.doi.org/10.1038/srep21304