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Identification of a nucleotide in 5′ untranslated region contributing to virus replication and virulence of Coxsackievirus A16

Coxsackievirus A16 (CA16) and enterovirus 71 (EV71) are two main causative pathogens of hand, foot and mouth disease (HFMD). Unlike EV71, virulence determinants of CA16, particularly within 5′ untranslated region (5′UTR), have not been investigated until now. Here, a series of nucleotides present in...

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Detalles Bibliográficos
Autores principales: Li, Zhaolong, Liu, Xin, Wang, Shaohua, Li, Jingliang, Hou, Min, Liu, Guanchen, Zhang, Wenyan, Yu, Xiao-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748407/
https://www.ncbi.nlm.nih.gov/pubmed/26861413
http://dx.doi.org/10.1038/srep20839