PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells

LF11-322 (PFWRIRIRR-NH(2)) (PFR peptide), a nine amino acid-residue peptide fragment derived from human lactoferricin, possesses potent cytotoxicity against bacteria. We report here the discovery and characterization of its antitumor activity in leukemia cells. PFR peptide inhibited the proliferatio...

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Detalles Bibliográficos
Autores principales: Lu, Yan, Zhang, Teng-Fei, Shi, Yue, Zhou, Han-Wei, Chen, Qi, Wei, Bu-Yun, Wang, Xi, Yang, Tian-Xin, Chinn, Y. Eugene, Kang, Jian, Fu, Cai-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748414/
https://www.ncbi.nlm.nih.gov/pubmed/26860588
http://dx.doi.org/10.1038/srep20823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748414/
https://www.ncbi.nlm.nih.gov/pubmed/26860588
http://dx.doi.org/10.1038/srep20823

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