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Hypersplenism in liver disease and SLE revisited: current evidence supports an active rather than passive process

BACKGROUND: Active and passive theories have been advanced to explain splenomegaly and cytopenias in liver disease. Dameshek proposed active downregulation of hematopoiesis. Doan proposed passive trapping of blood components in a spleen enlarged by portal hypertension. Recent findings do not support...

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Detalles Bibliográficos
Autores principales: Gemery, John M., Forauer, Andrew R., Silas, Anne M., Hoffer, Eric K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748462/
https://www.ncbi.nlm.nih.gov/pubmed/26865982
http://dx.doi.org/10.1186/s12878-016-0042-z