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Hypersplenism in liver disease and SLE revisited: current evidence supports an active rather than passive process
BACKGROUND: Active and passive theories have been advanced to explain splenomegaly and cytopenias in liver disease. Dameshek proposed active downregulation of hematopoiesis. Doan proposed passive trapping of blood components in a spleen enlarged by portal hypertension. Recent findings do not support...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748462/ https://www.ncbi.nlm.nih.gov/pubmed/26865982 http://dx.doi.org/10.1186/s12878-016-0042-z |