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Mutation pattern is an influential factor on functional mutation rates in cancer

BACKGROUND: Mutation rates are consistently varied in cancer genome and play an important role in tumorigenesis, however, little has been known about their function potential and impact on the distribution of functional mutations. In this study, we investigated genomic features which affect mutation...

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Detalles Bibliográficos
Autores principales: Du, Chuance, Wu, Xiaoyuan, Li, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748466/
https://www.ncbi.nlm.nih.gov/pubmed/26865835
http://dx.doi.org/10.1186/s12935-016-0278-5