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First-Line Use of Vemurafenib to Enable Thyroidectomy and Radioactive Iodine Ablation for BRAF-Positive Metastatic Papillary Thyroid Carcinoma: A Case Report

Background. Patients with metastatic or radioactive iodine refractory papillary thyroid carcinoma (PTC) have poor prognosis due to ineffective therapy for this condition beyond surgery and radioactive iodine (RAI or (131)I). BRAF mutation occurs in more than 44% of PCT. Tyrosine kinase inhibitors, t...

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Detalles Bibliográficos
Autores principales: Dao, Bao D., Lingvay, Ildiko, Sailors, Joseph, Landay, Michael, Shapiro, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748501/
https://www.ncbi.nlm.nih.gov/pubmed/26904701
http://dx.doi.org/10.1177/2324709615603723