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Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells
Kinetochores attach chromosomes to the spindle microtubules and signal the spindle assembly checkpoint to delay mitotic exit until all chromosomes are attached. Light microscopy approaches aimed to indirectly determine distances between various proteins within the kinetochore (termed Delta) suggest...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748573/ https://www.ncbi.nlm.nih.gov/pubmed/26833787 http://dx.doi.org/10.1083/jcb.201412139 |