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Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells

Kinetochores attach chromosomes to the spindle microtubules and signal the spindle assembly checkpoint to delay mitotic exit until all chromosomes are attached. Light microscopy approaches aimed to indirectly determine distances between various proteins within the kinetochore (termed Delta) suggest...

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Detalles Bibliográficos
Autores principales: Magidson, Valentin, He, Jie, Ault, Jeffrey G., O’Connell, Christopher B., Yang, Nachen, Tikhonenko, Irina, McEwen, Bruce F., Sui, Haixin, Khodjakov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748573/
https://www.ncbi.nlm.nih.gov/pubmed/26833787
http://dx.doi.org/10.1083/jcb.201412139