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High content screening application for cell-type specific behaviour in heterogeneous primary breast epithelial subpopulations

BACKGROUND: The complex interaction between multiple cell types and the microenvironment underlies the diverse pathways to carcinogenesis and necessitates sophisticated approaches to in vitro hypotheses testing. The combination of mixed culture format with high content immunofluorescence screening t...

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Detalles Bibliográficos
Autores principales: Johnston, Rebecca L., Wockner, Leesa, McCart Reed, Amy E., Wiegmans, Adrian, Chenevix-Trench, Georgia, Khanna, Kum Kum, Lakhani, Sunil R., Smart, Chanel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748588/
https://www.ncbi.nlm.nih.gov/pubmed/26861772
http://dx.doi.org/10.1186/s13058-016-0681-9