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High content screening application for cell-type specific behaviour in heterogeneous primary breast epithelial subpopulations
BACKGROUND: The complex interaction between multiple cell types and the microenvironment underlies the diverse pathways to carcinogenesis and necessitates sophisticated approaches to in vitro hypotheses testing. The combination of mixed culture format with high content immunofluorescence screening t...
Autores principales: | Johnston, Rebecca L., Wockner, Leesa, McCart Reed, Amy E., Wiegmans, Adrian, Chenevix-Trench, Georgia, Khanna, Kum Kum, Lakhani, Sunil R., Smart, Chanel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748588/ https://www.ncbi.nlm.nih.gov/pubmed/26861772 http://dx.doi.org/10.1186/s13058-016-0681-9 |
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