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Primary and recurrent diffuse astrocytomas: genomic profile comparison reveals acquisition of biologically relevant aberrations

BACKGROUND: Diffuse astrocytomas are characterized by their highly variable biological behavior. The possibility that tumors develop novel aberrations, with relevant biological properties, is often neglected. In this study, we present two cases of diffuse astrocytoma in which additional cytogenetic...

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Detalles Bibliográficos
Autores principales: Lhotska, Halka, Zemanova, Zuzana, Cechova, Hana, Ransdorfova, Sarka, Svobodova, Karla, Kramar, Filip, Krejcik, Zdenek, Michalova, Kyra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748601/
https://www.ncbi.nlm.nih.gov/pubmed/26865861
http://dx.doi.org/10.1186/s13039-016-0222-3