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Primary and recurrent diffuse astrocytomas: genomic profile comparison reveals acquisition of biologically relevant aberrations
BACKGROUND: Diffuse astrocytomas are characterized by their highly variable biological behavior. The possibility that tumors develop novel aberrations, with relevant biological properties, is often neglected. In this study, we present two cases of diffuse astrocytoma in which additional cytogenetic...
Autores principales: | Lhotska, Halka, Zemanova, Zuzana, Cechova, Hana, Ransdorfova, Sarka, Svobodova, Karla, Kramar, Filip, Krejcik, Zdenek, Michalova, Kyra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748601/ https://www.ncbi.nlm.nih.gov/pubmed/26865861 http://dx.doi.org/10.1186/s13039-016-0222-3 |
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