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circTAIL-seq, a targeted method for deep analysis of RNA 3′ tails, reveals transcript-specific differences by multiple metrics

Post-transcriptionally added RNA 3′ nucleotide extensions, or tails, impose numerous regulatory effects on RNAs, including effects on RNA turnover and translation. However, efficient methods for in-depth tail profiling of a transcript of interest are still lacking, hindering available knowledge part...

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Detalles Bibliográficos
Autores principales: Gazestani, Vahid H., Hampton, Marshall, Abrahante, Juan E., Salavati, Reza, Zimmer, Sara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748824/
https://www.ncbi.nlm.nih.gov/pubmed/26759453
http://dx.doi.org/10.1261/rna.054494.115