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Absence of diurnal variation in visceromotor response to colorectal distention in normal Long Evans rats

Background: Enhanced colorectal sensitivity (i.e. visceral hypersensitivity) is thought to be a pathophysiological mechanism in irritable bowel syndrome (IBS). In healthy men a circadian variation in rectal perception to colonic distention was described. Disturbed day and night rhythms, which occur...

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Detalles Bibliográficos
Autores principales: Botschuijver, Sara, Yu, Zhumei, Welting, Olaf, Cailotto, Cathy, Kalsbeek, Andries, van den Wijngaard, Rene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748828/
https://www.ncbi.nlm.nih.gov/pubmed/26925229
http://dx.doi.org/10.12688/f1000research.7238.1