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Single-Particle Cryo-EM of the Ryanodine Receptor Channel in an Aqueous Environment
Ryanodine receptors (RyRs) are tetrameric ligand-gated Ca(2+) release channels that are responsible for the increase of cytosolic Ca(2+) concentration leading to muscle contraction. Our current understanding of RyR channel gating and regulation is greatly limited due to the lack of a high-resolution...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748972/ https://www.ncbi.nlm.nih.gov/pubmed/26913144 http://dx.doi.org/10.4081/ejtm.2015.4803 |