Identification of CD112R as a novel checkpoint for human T cells

T cell immunoglobulin and ITIM domain (TIGIT) and CD226 emerge as a novel T cell cosignaling pathway in which CD226 and TIGIT serve as costimulatory and coinhibitory receptors, respectively, for the ligands CD155 and CD112. In this study, we describe CD112R, a member of poliovirus receptor–like prot...

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Detalles Bibliográficos
Autores principales: Zhu, Yuwen, Paniccia, Alessandro, Schulick, Alexander C., Chen, Wei, Koenig, Michelle R., Byers, Joshua T., Yao, Sheng, Bevers, Shaun, Edil, Barish H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749091/
https://www.ncbi.nlm.nih.gov/pubmed/26755705
http://dx.doi.org/10.1084/jem.20150785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749091/
https://www.ncbi.nlm.nih.gov/pubmed/26755705
http://dx.doi.org/10.1084/jem.20150785

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