The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites

Hepatitis C virus (HCV) is a positive-strand RNA virus of the Flaviviridae family and a major cause of liver disease worldwide. HCV replicates in the cytoplasm, and the synthesis of viral proteins induces extensive rearrangements of host cell membranes producing structures, collectively termed the m...

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Detalles Bibliográficos
Autores principales: Neufeldt, Christopher J., Joyce, Michael A., Van Buuren, Nicholas, Levin, Aviad, Kirkegaard, Karla, Gale Jr., Michael, Tyrrell, D. Lorne J., Wozniak, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749181/
https://www.ncbi.nlm.nih.gov/pubmed/26863439
http://dx.doi.org/10.1371/journal.ppat.1005428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749181/
https://www.ncbi.nlm.nih.gov/pubmed/26863439
http://dx.doi.org/10.1371/journal.ppat.1005428

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