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Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores

The aim of this study was to design, synthesize and validate a multifunctional antidepressant probe that is modified at two distinct positions. The purpose of these modifications was to allow covalent linkage of the probe to interaction partners, and decoration of probe-target complexes with fluores...

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Detalles Bibliográficos
Autores principales: Kirmeier, Thomas, Gopalakrishnan, Ranganath, Gormanns, Vanessa, Werner, Anna M., Cuboni, Serena, Rudolf, Georg C., Höfner, Georg, Wanner, Klaus T., Sieber, Stephan A., Schmidt, Ulrike, Holsboer, Florian, Rein, Theo, Hausch, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749225/
https://www.ncbi.nlm.nih.gov/pubmed/26863431
http://dx.doi.org/10.1371/journal.pone.0148608