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A Non-Synonymous Single Nucleotide Polymorphism in the HJURP Gene Associated with Susceptibility to Hepatocellular Carcinoma among Chinese

OBJECTIVE: HJURP (Holliday Junction-Recognizing Protein) plays dual roles in DNA repair and in accurate chromosome segregation during mitosis. We examined whether the single nucleotide polymorphisms (SNPs) of HJURP were associated with the risk of occurrence of hepatocellular carcinoma (HCC) among c...

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Detalles Bibliográficos
Autores principales: Huang, Wenfeng, Zhang, Hongxing, Hao, Yumin, Xu, Xiaobing, Zhai, Yun, Wang, Shaoxia, Li, Yang, Ma, Fuchao, Li, Yuanfeng, Wang, Zhifu, Zhang, Yang, Zhang, Xiumei, Liang, Renxiang, Wei, Zhongliang, Cui, Ying, Li, Yongqiang, Yu, Xinsen, Ji, Hongzan, He, Fuchu, Xie, Weimin, Zhou, Gangqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749235/
https://www.ncbi.nlm.nih.gov/pubmed/26863619
http://dx.doi.org/10.1371/journal.pone.0148618