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Strong Selection at MHC in Mexicans since Admixture

Mexicans are a recent admixture of Amerindians, Europeans, and Africans. We performed local ancestry analysis of Mexican samples from two genome-wide association studies obtained from dbGaP, and discovered that at the MHC region Mexicans have excessive African ancestral alleles compared to the rest...

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Detalles Bibliográficos
Autores principales: Zhou, Quan, Zhao, Liang, Guan, Yongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749250/
https://www.ncbi.nlm.nih.gov/pubmed/26863142
http://dx.doi.org/10.1371/journal.pgen.1005847