Mutagenicity in a Molecule: Identification of Core Structural Features of Mutagenicity Using a Scaffold Analysis

With advances in the development and application of Ames mutagenicity in silico prediction tools, the International Conference on Harmonisation (ICH) has amended its M7 guideline to reflect the use of such prediction models for the detection of mutagenic activity in early drug safety evaluation proc...

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Detalles Bibliográficos
Autores principales: Hsu, Kuo-Hsiang, Su, Bo-Han, Tu, Yi-Shu, Lin, Olivia A., Tseng, Yufeng J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749256/
https://www.ncbi.nlm.nih.gov/pubmed/26863515
http://dx.doi.org/10.1371/journal.pone.0148900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749256/
https://www.ncbi.nlm.nih.gov/pubmed/26863515
http://dx.doi.org/10.1371/journal.pone.0148900

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