Targeting matriptase in breast cancer abrogates tumor progression via impairment of stromal-epithelial growth factor signaling

Matriptase is an epithelia-specific membrane-anchored serine protease that has received considerable attention in recent years due to its consistent dysregulation in human epithelial tumors, including breast cancer. Mice with reduced levels of matriptase display a significant delay in oncogene-induc...

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Detalles Bibliográficos
Autores principales: Zoratti, Gina L., Tanabe, Lauren M., Varela, Fausto A., Murray, Andrew S., Bergum, Christopher, Colombo, Eloic, Lang, Julie, Molinolo, Alfredo A., Leduc, Richard, Marsault, Eric, Boerner, Julie, List, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749267/
https://www.ncbi.nlm.nih.gov/pubmed/25873032
http://dx.doi.org/10.1038/ncomms7776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749267/
https://www.ncbi.nlm.nih.gov/pubmed/25873032
http://dx.doi.org/10.1038/ncomms7776

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