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Targeting matriptase in breast cancer abrogates tumor progression via impairment of stromal-epithelial growth factor signaling
Matriptase is an epithelia-specific membrane-anchored serine protease that has received considerable attention in recent years due to its consistent dysregulation in human epithelial tumors, including breast cancer. Mice with reduced levels of matriptase display a significant delay in oncogene-induc...
Autores principales: | Zoratti, Gina L., Tanabe, Lauren M., Varela, Fausto A., Murray, Andrew S., Bergum, Christopher, Colombo, Eloic, Lang, Julie, Molinolo, Alfredo A., Leduc, Richard, Marsault, Eric, Boerner, Julie, List, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749267/ https://www.ncbi.nlm.nih.gov/pubmed/25873032 http://dx.doi.org/10.1038/ncomms7776 |
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