Pooled-Peptide Epitope Mapping Strategies Are Efficient and Highly Sensitive: An Evaluation of Methods for Identifying Human T Cell Epitope Specificities in Large-Scale HIV Vaccine Efficacy Trials

The interferon gamma, enzyme-linked immunospot (IFN-γ ELISpot) assay is widely used to identify viral antigen-specific T cells is frequently employed to quantify T cell responses in HIV vaccine studies. It can be used to define T cell epitope specificities using panels of peptide antigens, but with...

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Detalles Bibliográficos
Autores principales: Fiore-Gartland, Andrew, Manso, Bryce A., Friedrich, David P., Gabriel, Erin E., Finak, Greg, Moodie, Zoe, Hertz, Tomer, De Rosa, Stephen C., Frahm, Nicole, Gilbert, Peter B., McElrath, M. Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749288/
https://www.ncbi.nlm.nih.gov/pubmed/26863315
http://dx.doi.org/10.1371/journal.pone.0147812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749288/
https://www.ncbi.nlm.nih.gov/pubmed/26863315
http://dx.doi.org/10.1371/journal.pone.0147812

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