Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

Serotonergic anorexigens are the primary pharmacologic risk factor associated with pulmonary arterial hypertension (PAH), and the resulting PAH is clinically indistinguishable from the heritable form of disease, associated with BMPR2 mutations. Both BMPR2 mutation and agonists to the serotonin recep...

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Detalles Bibliográficos
Autores principales: West, James D., Carrier, Erica J., Bloodworth, Nathaniel C., Schroer, Alison K., Chen, Peter, Ryzhova, Larisa M., Gladson, Santhi, Shay, Sheila, Hutcheson, Joshua D., Merryman, W. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749293/
https://www.ncbi.nlm.nih.gov/pubmed/26863209
http://dx.doi.org/10.1371/journal.pone.0148657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749293/
https://www.ncbi.nlm.nih.gov/pubmed/26863209
http://dx.doi.org/10.1371/journal.pone.0148657

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