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Interferon-γ Is a Crucial Activator of Early Host Immune Defense against Mycobacterium ulcerans Infection in Mice

Buruli ulcer (BU), caused by infection with Mycobacterium ulcerans, is a chronic necrotizing human skin disease associated with the production of the cytotoxic macrolide exotoxin mycolactone. Despite extensive research, the type of immune responses elicited against this pathogen and the effector fun...

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Detalles Bibliográficos
Autores principales: Bieri, Raphael, Bolz, Miriam, Ruf, Marie-Thérèse, Pluschke, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749296/
https://www.ncbi.nlm.nih.gov/pubmed/26863011
http://dx.doi.org/10.1371/journal.pntd.0004450