Oral Efficacy of Apigenin against Cutaneous Leishmaniasis: Involvement of Reactive Oxygen Species and Autophagy as a Mechanism of Action

BACKGROUND: The treatment for leishmaniasis is currently based on pentavalent antimonials and amphotericin B; however, these drugs result in numerous adverse side effects. The lack of affordable therapy has necessitated the urgent development of new drugs that are efficacious, safe, and more accessi...

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Detalles Bibliográficos
Autores principales: Fonseca-Silva, Fernanda, Inacio, Job D. F., Canto-Cavalheiro, Marilene M., Menna-Barreto, Rubem F. S., Almeida-Amaral, Elmo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749305/
https://www.ncbi.nlm.nih.gov/pubmed/26862901
http://dx.doi.org/10.1371/journal.pntd.0004442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749305/
https://www.ncbi.nlm.nih.gov/pubmed/26862901
http://dx.doi.org/10.1371/journal.pntd.0004442

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