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Glycosylation of Residue 141 of Subtype H7 Influenza A Hemagglutinin (HA) Affects HA-Pseudovirus Infectivity and Sensitivity to Site A Neutralizing Antibodies

Human infections with H7 subtype influenza virus have been reported, including an H7N7 outbreak in Netherlands in 2003 and H7N9 infections in China in 2013. Previously, we reported murine monoclonal antibodies (mAbs) that recognize the antigenic site A of H7 hemagglutinin (HA). To better understand...

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Detalles Bibliográficos
Autores principales: Alvarado-Facundo, Esmeralda, Vassell, Russell, Schmeisser, Falko, Weir, Jerry P., Weiss, Carol D., Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749315/
https://www.ncbi.nlm.nih.gov/pubmed/26862918
http://dx.doi.org/10.1371/journal.pone.0149149