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RGD-Targeted Ultrasound Contrast Agent for Longitudinal Assessment of Hep-2 Tumor Angiogenesis In Vivo

OBJECTIVE: To prepare arginine-glycine-aspartate (RGD)-targeted ultrasound contrast microbubbles (MBs) and explore the feasibility of their use in assessing dynamic changes in αvβ3 integrin expression in a murine model of tumor angiogenesis. METHODS: RGD peptides were conjugated to the surfaces of m...

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Detalles Bibliográficos
Autores principales: Hu, Qiao, Wang, Xiao-Yan, Kang, Li-Ke, Wei, Hai-Ming, Xu, Chun-Mei, Wang, Tao, Wen, Zong-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749330/
https://www.ncbi.nlm.nih.gov/pubmed/26862757
http://dx.doi.org/10.1371/journal.pone.0149075