Detection of a Tumor Suppressor Gene Variant Predisposing to Colorectal Cancer in an 18th Century Hungarian Mummy

Mutations of the Adenomatous polyposis coli (APC) gene are common and strongly associated with the development of colorectal adenomas and carcinomas. While extensively studied in modern populations, reports on visceral tumors in ancient populations are scarce. To the best of our knowledge, genetic c...

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Detalles Bibliográficos
Autores principales: Feldman, Michal, Hershkovitz, Israel, Sklan, Ella H., Kahila Bar-Gal, Gila, Pap, Ildikó, Szikossy, Ildikó, Rosin-Arbesfeld, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749341/
https://www.ncbi.nlm.nih.gov/pubmed/26863316
http://dx.doi.org/10.1371/journal.pone.0147217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749341/
https://www.ncbi.nlm.nih.gov/pubmed/26863316
http://dx.doi.org/10.1371/journal.pone.0147217

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