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Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression

During cell division, progression through mitosis is driven by a protein phosphorylation wave. This wave namely depends on an activation-inactivation cycle of cyclin B-dependent kinase (Cdk) 1 while activities of major protein phosphatases, like PP1 and PP2A, appear directly or indirectly repressed...

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Detalles Bibliográficos
Autores principales: Della Monica, Rosa, Visconti, Roberta, Cervone, Nando, Serpico, Angela Flavia, Grieco, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749544/
https://www.ncbi.nlm.nih.gov/pubmed/26653855
http://dx.doi.org/10.7554/eLife.10399