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Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein

The majority of mitochondrial proteins are targeted to mitochondria by N-terminal presequences and use the TIM23 complex for their translocation across the mitochondrial inner membrane. During import, translocation through the channel in the inner membrane is coupled to the ATP-dependent action of a...

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Detalles Bibliográficos
Autores principales: Banerjee, Rupa, Gladkova, Christina, Mapa, Koyeli, Witte, Gregor, Mokranjac, Dejana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749553/
https://www.ncbi.nlm.nih.gov/pubmed/26714107
http://dx.doi.org/10.7554/eLife.11897