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ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation

Prdm14 is a sequence-specific transcriptional regulator of embryonic stem cell (ESC) pluripotency and primordial germ cell (PGC) formation. It exerts its function, at least in part, through repressing genes associated with epigenetic modification and cell differentiation. Here, we show that this rep...

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Detalles Bibliográficos
Autores principales: Nady, Nataliya, Gupta, Ankit, Ma, Ziyang, Swigut, Tomek, Koide, Akiko, Koide, Shohei, Wysocka, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749557/
https://www.ncbi.nlm.nih.gov/pubmed/26523391
http://dx.doi.org/10.7554/eLife.10150