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ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation
Prdm14 is a sequence-specific transcriptional regulator of embryonic stem cell (ESC) pluripotency and primordial germ cell (PGC) formation. It exerts its function, at least in part, through repressing genes associated with epigenetic modification and cell differentiation. Here, we show that this rep...
Autores principales: | Nady, Nataliya, Gupta, Ankit, Ma, Ziyang, Swigut, Tomek, Koide, Akiko, Koide, Shohei, Wysocka, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749557/ https://www.ncbi.nlm.nih.gov/pubmed/26523391 http://dx.doi.org/10.7554/eLife.10150 |
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