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Spatially coordinated dynamic gene transcription in living pituitary tissue

Transcription at individual genes in single cells is often pulsatile and stochastic. A key question emerges regarding how this behaviour contributes to tissue phenotype, but it has been a challenge to quantitatively analyse this in living cells over time, as opposed to studying snap-shots of gene ex...

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Detalles Bibliográficos
Autores principales: Featherstone, Karen, Hey, Kirsty, Momiji, Hiroshi, McNamara, Anne V, Patist, Amanda L, Woodburn, Joanna, Spiller, David G, Christian, Helen C, McNeilly, Alan S, Mullins, John J, Finkenstädt, Bärbel F, Rand, David A, White, Michael RH, Davis, Julian RE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749562/
https://www.ncbi.nlm.nih.gov/pubmed/26828110
http://dx.doi.org/10.7554/eLife.08494