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Spatially coordinated dynamic gene transcription in living pituitary tissue
Transcription at individual genes in single cells is often pulsatile and stochastic. A key question emerges regarding how this behaviour contributes to tissue phenotype, but it has been a challenge to quantitatively analyse this in living cells over time, as opposed to studying snap-shots of gene ex...
Autores principales: | Featherstone, Karen, Hey, Kirsty, Momiji, Hiroshi, McNamara, Anne V, Patist, Amanda L, Woodburn, Joanna, Spiller, David G, Christian, Helen C, McNeilly, Alan S, Mullins, John J, Finkenstädt, Bärbel F, Rand, David A, White, Michael RH, Davis, Julian RE |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749562/ https://www.ncbi.nlm.nih.gov/pubmed/26828110 http://dx.doi.org/10.7554/eLife.08494 |
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