Evaluation of anticonvulsant and antinociceptive properties of new N-Mannich bases derived from pyrrolidine-2,5-dione and 3-methylpyrrolidine-2,5-dione

The aim of the present experiments was to examine anticonvulsant activity of new pyrrolidine-2,5-dione and 3-methylpyrrolidine-2,5-dione derivatives in animal models of epilepsy. In addition, the possible collateral antinociceptive activity was assessed. Anticonvulsant activity was investigated in t...

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Detalles Bibliográficos
Autores principales: Rapacz, Anna, Rybka, Sabina, Obniska, Jolanta, Sałat, Kinga, Powroźnik, Beata, Pękala, Elżbieta, Filipek, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749642/
https://www.ncbi.nlm.nih.gov/pubmed/26650502
http://dx.doi.org/10.1007/s00210-015-1194-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749642/
https://www.ncbi.nlm.nih.gov/pubmed/26650502
http://dx.doi.org/10.1007/s00210-015-1194-2

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