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mTOR is essential for corticosteroid effects on hippocampal AMPA receptor function and fear memory

Glucocorticoid hormones, via activation of their receptors, promote memory consolidation, but the exact underlying mechanisms remain elusive. We examined how corticosterone regulates AMPA receptors (AMPARs), which are crucial for synaptic plasticity and memory formation. Combining a live imaging flu...

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Detalles Bibliográficos
Autores principales: Xiong, Hui, Cassé, Frédéric, Zhou, Yang, Zhou, Ming, Xiong, Zhi-Qi, Joëls, Marian, Martin, Stéphane, Krugers, Harm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749735/
https://www.ncbi.nlm.nih.gov/pubmed/26572647
http://dx.doi.org/10.1101/lm.039420.115