Cargando…

mTOR is essential for corticosteroid effects on hippocampal AMPA receptor function and fear memory

Glucocorticoid hormones, via activation of their receptors, promote memory consolidation, but the exact underlying mechanisms remain elusive. We examined how corticosterone regulates AMPA receptors (AMPARs), which are crucial for synaptic plasticity and memory formation. Combining a live imaging flu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Hui, Cassé, Frédéric, Zhou, Yang, Zhou, Ming, Xiong, Zhi-Qi, Joëls, Marian, Martin, Stéphane, Krugers, Harm J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749735/ https://www.ncbi.nlm.nih.gov/pubmed/26572647 http://dx.doi.org/10.1101/lm.039420.115

Ejemplares similares

Regulation of Excitatory Synapses and Fearful Memories by Stress Hormones
por: Krugers, Harm J., et al.
Publicado: (2011)

Blocking Mineralocorticoid Receptors prior to Retrieval Reduces Contextual Fear Memory in Mice
por: Zhou, Ming, et al.
Publicado: (2011)

Interactions between noradrenaline and corticosteroids in the brain: from electrical activity to cognitive performance
por: Krugers, Harm J., et al.
Publicado: (2012)

LTP after Stress: Up or Down?
por: Joëls, Marian, et al.
Publicado: (2007)

Overexpression of Mineralocorticoid Receptors Partially Prevents Chronic Stress-Induced Reductions in Hippocampal Memory and Structural Plasticity
por: Kanatsou, Sofia, et al.
Publicado: (2015)

Correction: Overexpression of Mineralocorticoid Receptors Partially Prevents Chronic Stress-Induced Reductions in Hippocampal Memory and Structural Plasticity
por: Kanatsou, Sofia, et al.
Publicado: (2015)

Hormonal Regulation of AMPA Receptor Trafficking and Memory Formation
por: Krugers, Harmen J., et al.
Publicado: (2009)

Chronic Stress Effects on Hippocampal Structure and Synaptic Function: Relevance for Depression and Normalization by Anti-Glucocorticoid Treatment
por: Krugers, Harmen J., et al.
Publicado: (2010)

Dendritic Morphology of Hippocampal and Amygdalar Neurons in Adolescent Mice Is Resilient to Genetic Differences in Stress Reactivity
por: Pillai, Anup G., et al.
Publicado: (2012)

Overexpression of mineralocorticoid receptors does not affect memory and anxiety-like behavior in female mice
por: Kanatsou, Sofia, et al.
Publicado: (2015)

Fear memory formation can affect a different memory: fear conditioning affects the extinction, but not retrieval, of conditioned taste aversion (CTA) memory
por: Joels, Gil, et al.
Publicado: (2014)

Prolonged contextual fear memory in AMPA receptor palmitoylation-deficient mice
por: Oota-Ishigaki, Akiko, et al.
Publicado: (2022)

Early life adversity: Lasting consequences for emotional learning
por: Krugers, Harm J., et al.
Publicado: (2016)

Effects of Early Life Stress on Synaptic Plasticity in the Developing Hippocampus of Male and Female Rats
por: Derks, Nienke A. V., et al.
Publicado: (2016)

Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington’s disease models
por: Zhang, Hongyu, et al.
Publicado: (2018)

Effects of Mineralocorticoid Receptor Overexpression on Anxiety and Memory after Early Life Stress in Female Mice
por: Kanatsou, Sofia, et al.
Publicado: (2016)

Overexpression of Mineralocorticoid Receptors in the Mouse Forebrain Partly Alleviates the Effects of Chronic Early Life Stress on Spatial Memory, Neurogenesis and Synaptic Function in the Dentate Gyrus
por: Kanatsou, Sofia, et al.
Publicado: (2017)

Hippocampal awake replay in fear memory retrieval
por: Wu, Chun-Ting, et al.
Publicado: (2017)

Hippocampal Administration of Levothyroxine Impairs Contextual Fear Memory Consolidation in Rats
por: Yu, Dafu, et al.
Publicado: (2017)

AMPA Receptor–mTOR Activation is Required for the Antidepressant-Like Effects of Sarcosine during the Forced Swim Test in Rats: Insertion of AMPA Receptor may Play a Role
por: Chen, Kuang-Ti, et al.
Publicado: (2015)

Slow AMPA receptors in hippocampal principal cells
por: Pampaloni, Niccolò P., et al.
Publicado: (2021)

Mineralocorticoid Receptors Guide Spatial and Stimulus-Response Learning in Mice
por: Arp, J. Marit, et al.
Publicado: (2014)

IGF1-Stimulated Posttraumatic Hippocampal Remodeling Is Not Dependent on mTOR
por: Littlejohn, Erica L., et al.
Publicado: (2021)

The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory
por: Schmitz, Leanne J M, et al.
Publicado: (2017)

Hippocampal Long-Term Depression in the Presence of Calcium-Permeable AMPA Receptors
por: Cao, Feng, et al.
Publicado: (2018)

T memory stem cell formation: Caveat mTOR
por: Fowler, Daniel H., et al.
Publicado: (2016)

mTOR inhibition impairs extinction memory reconsolidation
por: Radiske, Andressa, et al.
Publicado: (2021)

Opposite Effects of Early Maternal Deprivation on Neurogenesis in Male versus Female Rats
por: Oomen, Charlotte A., et al.
Publicado: (2009)

Encoding of contextual fear memory in hippocampal–amygdala circuit
por: Kim, Woong Bin, et al.
Publicado: (2020)

Fear memory recall involves hippocampal somatostatin interneurons
por: Zichó, Krisztián, et al.
Publicado: (2023)

GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons
por: Gu, Xinglong, et al.
Publicado: (2016)

Temporal changes in mammalian target of rapamycin (mTOR) and phosphorylated-mTOR expressions in the hippocampal CA1 region of rat with vascular dementia
por: Park, Jin-A, et al.
Publicado: (2017)

Correction: The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory
por: Schmitz, Leanne J M, et al.
Publicado: (2018)

Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits
por: Alhowail, Ahmad H., et al.
Publicado: (2021)

PS114. Effects of Tianeptine on mTOR Signaling in Rat Hippocampal Neurons
por: Seo, Mi Kyoung, et al.
Publicado: (2016)

Phosphorylated Mammalian Target of Rapamycin p-mTOR Is a Favorable Prognostic Factor than mTOR in Gastric Cancer
por: Cao, Guo-dong, et al.
Publicado: (2016)

Fear Memory Retrieval Is Associated With a Reduction in AMPA Receptor Density at Thalamic to Amygdala Intercalated Cell Synapses
por: Seewald, Anna, et al.
Publicado: (2021)

Glucocorticoid and β‐adrenergic regulation of hippocampal dendritic spines
por: Lesuis, Sylvie L., et al.
Publicado: (2019)

Hippocampal Synthesis of Sex Steroids and Corticosteroids: Essential for Modulation of Synaptic Plasticity
por: Hojo, Yasushi, et al.
Publicado: (2011)

mTOR regulates memory CD8 T cell differentiation
por: Araki, Koichi, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_nrre843plpg8p3qr7iu79o7rkf