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Glucosamine Hydrochloride but Not Chondroitin Sulfate Prevents Cartilage Degradation and Inflammation Induced by Interleukin-1α in Bovine Cartilage Explants

OBJECTIVE: Glucosamine hydrochloride (GH) and chondroitin sulfate (CS) are commonly used for the treatment of osteoarthritis (OA). The aim of this study was to assess their effects, alone and in combination, on preventing aggrecan degradation and inflammation in an in vitro model of OA. DESIGN: To t...

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Detalles Bibliográficos
Autores principales: Bascoul-Colombo, Cécile, Garaiova, Iveta, Plummer, Sue F., Harwood, John L., Caterson, Bruce, Hughes, Clare E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749751/
https://www.ncbi.nlm.nih.gov/pubmed/26958319
http://dx.doi.org/10.1177/1947603515603762