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E2A Antagonizes PU.1 Activity through Inhibition of DNA Binding

Antagonistic interactions between transcription factors contribute to cell fate decisions made by multipotent hematopoietic progenitor cells. Concentration of the transcription factor PU.1 affects myeloid/lymphoid development with high levels of PU.1 directing myeloid cell fate acquisition at the ex...

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Detalles Bibliográficos
Autores principales: Rogers, Jason H., Owens, Kristin S., Kurkewich, Jeffrey, Klopfenstein, Nathan, Iyer, Sangeeta R., Simon, M. Celeste, Dahl, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749766/
https://www.ncbi.nlm.nih.gov/pubmed/26942192
http://dx.doi.org/10.1155/2016/3983686