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Lack of Proinflammatory Cytokine Interleukin-6 or Tumor Necrosis Factor Receptor-1 Results in a Failure of the Innate Immune Response after Bacterial Meningitis

The most frequent pathogen that causes bacterial meningitis is the Gram-positive bacterium Streptococcus pneumoniae. By entering the brain, host cells will be activated and proinflammatory cytokines like interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are released. The goal of the current s...

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Detalles Bibliográficos
Autores principales: Albrecht, Lea-Jessica, Tauber, Simone C., Merres, Julika, Kress, Eugenia, Stope, Matthias B., Jansen, Sandra, Pufe, Thomas, Brandenburg, Lars-Ove
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749820/
https://www.ncbi.nlm.nih.gov/pubmed/27057100
http://dx.doi.org/10.1155/2016/7678542