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Targeted deletion of miR-132/-212 impairs memory and alters the hippocampal transcriptome

miR-132 and miR-212 are structurally related microRNAs that have been found to exert powerful modulatory effects within the central nervous system (CNS). Notably, these microRNAs are tandomly processed from the same noncoding transcript, and share a common seed sequence: thus it has been difficult t...

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Detalles Bibliográficos
Autores principales: Hansen, Katelin F., Sakamoto, Kensuke, Aten, Sydney, Price, Kaiden H., Loeser, Jacob, Hesse, Andrea M., Page, Chloe E., Pelz, Carl, Arthur, J. Simon C., Impey, Soren, Obrietan, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749831/
https://www.ncbi.nlm.nih.gov/pubmed/26773099
http://dx.doi.org/10.1101/lm.039578.115