Metabolic disruption identified in the Huntington’s disease transgenic sheep model

Huntington’s disease (HD) is a dominantly inherited, progressive neurodegenerative disorder caused by a CAG repeat expansion within exon 1 of HTT, encoding huntingtin. There are no therapies that can delay the progression of this devastating disease. One feature of HD that may play a critical role i...

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Detalles Bibliográficos
Autores principales: Handley, Renee. R., Reid, Suzanne J., Patassini, Stefano, Rudiger, Skye R., Obolonkin, Vladimir, McLaughlan, Clive. J., Jacobsen, Jessie C., Gusella, James F., MacDonald, Marcy E., Waldvogel, Henry J., Bawden, C. Simon, Faull, Richard L. M., Snell, Russell G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749952/
https://www.ncbi.nlm.nih.gov/pubmed/26864449
http://dx.doi.org/10.1038/srep20681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749952/
https://www.ncbi.nlm.nih.gov/pubmed/26864449
http://dx.doi.org/10.1038/srep20681

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