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Comprehensive behavioral analysis of RNG105 (Caprin1) heterozygous mice: Reduced social interaction and attenuated response to novelty

RNG105 (also known as Caprin1) is a major RNA-binding protein in neuronal RNA granules, and is responsible for mRNA transport to dendrites and neuronal network formation. A recent study reported that a heterozygous mutation in the Rng105 gene was found in an autism spectrum disorder (ASD) patient, b...

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Detalles Bibliográficos
Autores principales: Ohashi, Rie, Takao, Keizo, Miyakawa, Tsuyoshi, Shiina, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749962/
https://www.ncbi.nlm.nih.gov/pubmed/26865403
http://dx.doi.org/10.1038/srep20775