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Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

Cells routinely compartmentalize enzymes for enhanced efficiency of their metabolic pathways. Here we report a general approach to construct DNA nanocaged enzymes for enhancing catalytic activity and stability. Nanocaged enzymes are realized by self-assembly into DNA nanocages with well-controlled s...

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Detalles Bibliográficos
Autores principales: Zhao, Zhao, Fu, Jinglin, Dhakal, Soma, Johnson-Buck, Alexander, Liu, Minghui, Zhang, Ting, Woodbury, Neal W., Liu, Yan, Walter, Nils G., Yan, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749968/
https://www.ncbi.nlm.nih.gov/pubmed/26861509
http://dx.doi.org/10.1038/ncomms10619