Alp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism

Alp14 is a TOG-family microtubule polymerase from S. pombe that tracks plus ends and accelerates their growth. To interrogate its mechanism, we reconstituted dynamically unstable single isoform S. pombe microtubules with full length Alp14/TOG and Alp7, the TACC-family binding partner of Alp14. We fi...

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Detalles Bibliográficos
Autores principales: Hussmann, Frauke, Drummond, Douglas R., Peet, Daniel R., Martin, Douglas S., Cross, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749977/
https://www.ncbi.nlm.nih.gov/pubmed/26864000
http://dx.doi.org/10.1038/srep20653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749977/
https://www.ncbi.nlm.nih.gov/pubmed/26864000
http://dx.doi.org/10.1038/srep20653

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