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ITF2357 transactivates Id3 and regulate TGFβ/BMP7 signaling pathways to attenuate corneal fibrosis

Corneal fibrosis is often seen in patients with ocular trauma and infection that compromises corneal transparency resulting in vision loss. Treatment strategies including NSAIDs, steroids, MMC and corneal transplants have shown tremendous success but with several side effects and cellular toxicity....

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Detalles Bibliográficos
Autores principales: Lim, Rayne R., Tan, Alison, Liu, Yu-Chi, Barathi, Veluchamy A., Mohan, Rajiv R., Mehta, Jodhbir S., Chaurasia, Shyam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750002/
https://www.ncbi.nlm.nih.gov/pubmed/26865052
http://dx.doi.org/10.1038/srep20841